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Thiazide (hydrochlorothiazide,...) and thiazide-like (chlortalidone, indapamide,...) diuretics are widely used to treat hypertensive patients. There is growing evidence that these diuretics are not interchangeable and that it might be preferable to choose a thiazide-like diuretic whenever the use of a diuretic is considered. This is in order to prevent optimally the development of cardiovascular complications and the occurrence of metabolic side effects, in particular diabetes.

Citation

B Waeber, F Feihl. Are all diuretics equal for the treatment of hypertensive patients?]. Revue m├ędicale suisse. 2012 Sep 12;8(353):1699-701

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PMID: 23029982

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