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Cushing disease (CD) is caused by overproduction of adrenocorticotropin by a pituitary adenoma (or, rarely, carcinoma). The diagnosis of CD requires distinguishing it from other hypercortisolemic states with a thorough endocrine workup. CD remains a primarily surgical disease, with remission rates of 70% to 95% following microscopic or endoscopic transsphenoidal surgery. Copyright © 2012 Elsevier Inc. All rights reserved.


Sameer A Sheth, Sarah K Bourne, Nicholas A Tritos, Brooke Swearingen. Neurosurgical treatment of Cushing disease. Neurosurgery clinics of North America. 2012 Oct;23(4):639-51

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PMID: 23040749

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