DNA nanostructure meets nanofabrication.

Guomei Zhang, Sumedh P Surwade, Feng Zhou, Haitao Liu

School of Chemistry and Chemical Engineering, Center of Environmental Science and Engineering Research, Shanxi University, Taiyuan, 030006, P.R. China.

Chemical Society reviews 2013 Apr 7

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Recent advances in DNA nanotechnology have made it possible to construct DNA nanostructures of almost arbitrary shapes with 2-3 nm of precision in their dimensions. These DNA nanostructures are ideal templates for bottom-up nanofabrication. This review highlights the challenges and recent advances in three areas that are directly related to DNA-based nanofabrication: (1) fabrication of large scale DNA nanostructures; (2) pattern transfer from DNA nanostructure to an inorganic substrate; and (3) directed assembly of DNA nanostructures.