S Takase, I Uchida, S Hashimoto, H Tanaka, M Hashimoto
Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Ibaraki, Japan.
The Journal of antibiotics 1990 JanThe structures of WS1358A1 and B1, new dehydropeptidase inhibitors isolated from Streptomyces parvulus subsp. tochigiensis No. 1358, have been established to be 2-hydroxy-2-hydroxyaminocarbonyl-3-methylglutaric acid (1) and 2-hydroxy-2-hydroxyaminocarbonylglutaric acid (2), respectively, on the basis of spectroscopic evidence and synthesis of the racemates.
S Takase, I Uchida, S Hashimoto, H Tanaka, M Hashimoto. Studies on new dehydropeptidase inhibitors. II. Structural elucidation and synthesis of WS1358A1 and B1. The Journal of antibiotics. 1990 Jan;43(1):38-42
PMID: 2307629
View Full Text