Acylcarnitine profile in thyroid disease.

Sophia Wong, Fady Hannah-Shmouni, Graham Sinclair, Sandra Sirrs, Marshall Dahl, Andre Mattman

Division of Medical Biochemistry, Department of Pathology and Laboratory Medicine, St. Paul's Hospital, Vancouver, Canada. Wong.Sophia@gmail.com

Clinical biochemistry 2013 Jan

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To examine acylcarnitine profiles in individuals with hypo- or hyperthyroidism, and determine whether any atypical acylcarnitine species identified would normalize with correction of thyroid status. Serum acylcarnitine levels were measured in hypo- and hyperthyroid subjects before and after treatment with thyroxine or thionamide therapy respectively. No discernible differences were observed in the serum acylcarnitine profiles between hypo-, hyper- and euthyroid states. Acylcarnitine profiles are relatively unremarkable in thyroid disease. Copyright © 2012 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

Citation

Sophia Wong, Fady Hannah-Shmouni, Graham Sinclair, Sandra Sirrs, Marshall Dahl, Andre Mattman. Acylcarnitine profile in thyroid disease. Clinical biochemistry. 2013 Jan;46(1-2):180-3