The tf (tufted) locus is responsible for a classic phenotype of hair loss and regrowth in mice. It is a characteristic of the BTBR strain. Here, we use a combination of positional cloning methods and complementation mapping to identify Itpr3, the inositol triphosphate receptor type 3, as the gene responsible for the tf locus.
Hillary T Ellis, Michael G Tordoff, M Rockwell Parker. Itpr3 Is responsible for the mouse tufted (tf) locus. The Journal of heredity. 2013 Mar;104(2):295-7
PMID: 23100490
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