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Azobisisobutyronitrile initiated aerobic oxidative transformation of amines: coupling of primary amines and cyanation of tertiary amines.
Lianghui Liu, Zikuan Wang, Xuefeng Fu, Chun-Hua Yan
Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, PR China.
Organic letters 2012 Nov 16Sizes of these terms reflect their relevance to your search.
In the presence of a catalytic amount of radical initiator AIBN, primary amines are oxidatively coupled to imines and tertiary amines are cyanated to α-aminonitriles. These "metal-free" aerobic oxidative coupling reactions may find applications in a wide range of "green" oxidation chemistry.
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Lianghui Liu, Zikuan Wang, Xuefeng Fu, Chun-Hua Yan. Azobisisobutyronitrile initiated aerobic oxidative transformation of amines: coupling of primary amines and cyanation of tertiary amines. Organic letters. 2012 Nov 16;14(22):5692-5
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PMID: 23106189
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