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Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond® supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann-Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level (P<0.001). Copyright © 2013 Elsevier Inc. All rights reserved.


Yaser El-Gazzar, Daniel C Smith, Sun Jin Kim, David M Hirsh, Yossef Blum, Marcie Cobelli, Hillel W Cohen. The use of dermabond® as an adjunct to wound closure after total knee arthroplasty: examining immediate post-operative wound drainage. The Journal of arthroplasty. 2013 Apr;28(4):553-6

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PMID: 23114193

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