Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin.

Arlene C Seña, Mark Wolff, Frieda Behets, Kathleen Van Damme, David H Martin, Peter Leone, Linda McNeil, Edward W Hook

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2013 Feb

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Persistent nontreponemal titers after treatment are common among patients with early syphilis. We retreated 82 human immunodeficiency virus-negative early syphilis participants who were serofast at 6 months using benzathine penicillin. Only 27% exhibited serological response after retreatment and after an additional 6 months of follow-up.

Citation

Arlene C Seña, Mark Wolff, Frieda Behets, Kathleen Van Damme, David H Martin, Peter Leone, Linda McNeil, Edward W Hook. Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2013 Feb;56(3):420-2