Clear Search sequence regions


Sizes of these terms reflect their relevance to your search.

Lowering intra-ocular pressure, either medically or surgically, is the proven strategy to control glaucoma, though profound changes to the ocular surface and conjunctiva are caused. Toxicity and allergy initiated by medical therapy induce modifications, which progressively worsen with the length of treatment and number of drugs. Conjunctival changes lead to symptoms of ocular surface disease, reduced quality of life, reduced therapeutic compliance and increased risk of surgical failure. Surgery modifies conjunctiva by inducing bleb formation in fistulizing techniques, and by activating secondary aqueous humour outflow pathways, such as trans-scleral routes, in both filtration and bleb-less approaches. The use of unpreserved medications, limitation of intra-operative conjunctival damage and development of bleb-less surgery are advisable. Copyright © 2012 Elsevier Ltd. All rights reserved.

Citation

Leonardo Mastropasqua, Luca Agnifili, Rodolfo Mastropasqua, Vincenzo Fasanella. Conjunctival modifications induced by medical and surgical therapies in patients with glaucoma. Current opinion in pharmacology. 2013 Feb;13(1):56-64

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 23127698

View Full Text