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We investigated the cytotoxicity of the fullerene C60 derivatives. We showed that complexes of C60 fullerene with polyvinylpyrrolidone (m.w. of polyvinylpyrrolidone 10000 and 25000), C60-NO2-proline and C60-alanine had no toxic effect on HEp-2 cells. Sodium salt of polycarboxylic derivative of fullerene C60 exerted a pronounced toxic effect on this cell culture.

Citation

A G Bobylëv, A D Okuneva, L G Bobylëva, I S Fadeeva, R S Fadeev, N N Salmov, Z A Poddubnaia. Study of cytotoxicity of fullerene C60 derivatives]. Biofizika. 2012 Sep-Oct;57(5):746-50

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PMID: 23136765

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