Role of kruppel-like transcription factors in adipogenesis.

Zeni Wu, Suqing Wang

School of Public Health, Wuhan University, Wuhan, China.

Developmental biology 2013 Jan 15

filter terms:

The zinc-finger transcription factors of the kruppel-like factor family (KLF) are critical in many physiological and pathological processes including cell proliferation, differentiation, inflammation, and apoptosis. Recently, there is increasing evidence that suggests these KLFs have an important role in fat biology. This review summarizes the role of KLFs in lipid metabolism, especially in adipogenesis, and reveals the relationship networks among members of KLF family in differentiation. Copyright © 2012 Elsevier Inc. All rights reserved.