Institute for Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany.
Methods in molecular biology (Clifton, N.J.) 2013The animal model of N-methyl-D-aspartate (NMDA)-induced excitotoxic damage of retinal ganglion cells (RGC) is widely used to study the molecular mechanisms of RGC apoptosis and/or its prevention by neuroprotective agents. This chapter provides protocols for applying NMDA-induced excitotoxic damage to RGC of mouse eyes and for subsequent measuring of the extent of the resulting damage.
Roswitha Seitz, Ernst R Tamm. N-methyl-D-aspartate (NMDA)-mediated excitotoxic damage: a mouse model of acute retinal ganglion cell damage. Methods in molecular biology (Clifton, N.J.). 2013;935:99-109
PMID: 23150363
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