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The tolerability of amphotericin B lipid complex in patients with previous severe infusion reactions to liposomal amphotericin B is unclear. We reviewed the charts of 40 such patients at a tertiary care cancer center and found that amphotericin B lipid complex administration was uneventful in 34 patients (85% [95% confidence interval, 69%-93%]).

Citation

Dimitrios Farmakiotis, Frank P Tverdek, Dimitrios P Kontoyiannis. The safety of amphotericin B lipid complex in patients with prior severe intolerance to liposomal amphotericin B. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2013 Mar;56(5):701-3

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PMID: 23166189

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