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Synthesis and use of a trifluoromethylated azomethine ylide precursor.
Gaël Tran, Robin Meier, Lawrence Harris, Duncan L Browne, Steven V Ley
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.
The Journal of organic chemistry 2012 Dec 21Sizes of these terms reflect their relevance to your search.
The presence of fluorous substituents can impart a dramatic effect on the efficacy of molecules used for a range of applications in society. Here, we describe the preparation and use of a new trifluoromethylated azomethine ylide precursor, which leads to a series of fluorinated pyrrolidine, 3-pyrroline, and pyrrole building blocks.
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Gaël Tran, Robin Meier, Lawrence Harris, Duncan L Browne, Steven V Ley. Synthesis and use of a trifluoromethylated azomethine ylide precursor. The Journal of organic chemistry. 2012 Dec 21;77(24):11071-8
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PMID: 23176732
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