Correlation Engine 2.0
Clear Search sequence regions

Dermatophagoides pteronyssinus specific IgE (sIgE) measurement is a major diagnostic test for the detection of sensitization to that allergen. To investigate the effect of climate on the seasonal variations of D.pteronyssinus sIgE, we studied the tests performed in an insular population during a 10-year period. The association with meteorological factors was evaluated with multiple regression analyses. Of 24,879 tests performed for D. pteronyssinus sIgE, 16,719 (67.2%) were D. pteronyssinus sIgE positive; 24.5% were tested for asthma and 46.07% for rhinitis. D. pteronyssinus sIgE levels showed a seasonal pattern with an annual peak in November. In the multivariate analyses solar radiation (r = -0.94) and relative humidity (r = 0.86) were independent factors associated with D. pteronyssinus sIgE levels. The resulting model could explain 93% (p < 0.001) of D. pteronyssinus sIgE variability. Our population showed a seasonal pattern of D. pteronyssinus sIgE explained by relative humidity and solar radiation. Copyright © 2012 S. Karger AG, Basel.


D Hervás, J Pons, J Milá, N Matamoros, J A Hervás, L García-Marcos. Specific IgE levels to Dermatophagoides pteronyssinus are associated with meteorological factors. International archives of allergy and immunology. 2013;160(4):383-6

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 23183329

View Full Text