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Genital self-mutilation is a well-known phenomenon in patients with schizophrenia and has occasionally been described in patients with personality disorders or transsexuality. However, literature just provides few cases of genital self-mutilation related to the use of psychotropic substances. A previously mentally healthy man (age, 32 years) performed manual amputation of both testes after first use of lysergic acid diethylamide in combination with alcohol consumption. Follow-up examination 6 month after the event did not reveal the development of a psychiatric disorder. This report shows that a first and single use of lysergic acid diethylamide in combination with alcohol can cause intoxication with dramatic consequences.


Christian Blacha, Markus M Schmid, Maximilian Gahr, Roland W Freudenmann, Paul L Plener, Florian Finter, Bernhard J Connemann, Carlos Schönfeldt-Lecuona. Self-inflicted testicular amputation in first lysergic acid diethylamide use. Journal of addiction medicine. 2013 Jan-Feb;7(1):83-4

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PMID: 23222128

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