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A 65-year-old man was referred to our hospital because of an elevated value of prostate specific antigen (PSA) (10.9 ng/ml). An eight-core prostate biopsy was negative. One year later, serum PSA increased to 55. 8 ng/ml and pelvic magnetic resonance imaging (MRI) showed a left external iliac lymph node enlargement. A ten-core prostate biopsy was negative. Six months later, the serum PSA increased to 88.1 ng/ml, but an seventeen-core prostate biopsy was negative again. A positron emission tomographycomputed tomography scan showed nothing other than increased uptake localized to the left enlarged external iliac lymph node. Pelvic lymphadenectomy was performed and histological examination, including immunohistological staining with PSA, confirmed lymph node metastasis from prostate cancer. Androgen deprivation therapy was started and 2 month later, serum PSA declined to below 1.0 ng/ml.


Ryo Fukumoto, Tetsuji Soda, Mitsuru Uehara, Tetsuya Hayashi, Daizo Oka, Nobumasa Fujimoto, Takuo Koide. A case of prostate cancer diagnosed by lymphadenectomy]. Hinyokika kiyo. Acta urologica Japonica. 2012 Oct;58(10):557-60

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PMID: 23235279

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