Association of candidate gene polymorphisms with diastolic blood pressure change in patients treated with duloxetine.

Bonnie Ann Fijal, Jared Kohler, Katherine Ostbye, Jonna Ahl, John Phillip Houston

Global Statistics and Advanced Analytics, Lilly USA, LLC, Mail Code 4103, Indianapolis, IN, USA. fijal_bonnie_ann@lilly.com

Psychiatry research 2013 Apr 30

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Single nucleotide polymorphisms in six genes were investigated for an association between diastolic blood pressure change and duloxetine treatment. Nominally significant within-gene association was found with SLC6A2 rs4436775 and rs4564560 and HTR2A rs6313, but after adjusting for multiple comparisons, these associations were no longer significant. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Citation

Bonnie Ann Fijal, Jared Kohler, Katherine Ostbye, Jonna Ahl, John Phillip Houston. Association of candidate gene polymorphisms with diastolic blood pressure change in patients treated with duloxetine. Psychiatry research. 2013 Apr 30;206(2-3):313-4