Modulation of myocardial contraction by peroxynitrite.

Mark J Kohr, Steve R Roof, Jay L Zweier, Mark T Ziolo

Frontiers in physiology 2012

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Peroxynitrite is a potent oxidant that is quickly emerging as a crucial modulator of myocardial function. This review will focus on the regulation of myocardial contraction by peroxynitrite during health and disease, with a specific emphasis on cardiomyocyte Ca(2+) handling, proposed signaling pathways, and protein end-targets.

Citation

Mark J Kohr, Steve R Roof, Jay L Zweier, Mark T Ziolo. Modulation of myocardial contraction by peroxynitrite. Frontiers in physiology. 2012;3:468

PMID: 23248603

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