Study on chemical constituents from the root bark of Tripterygium hypoglaucum].

Fu-Gui Xie, Chuang-Jun Li, Jing-Zhi Yang, Yong-Ming Luo, Dong-Ming Zhang

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China. xiefugui01@163.com

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 2012 Jul

filter terms:

To study the chemical constituents of the root bark of Tripterygium hypoglaucum. Column chromatography was used to separate the chemical constituents. The structures were determined by application of spectroscopic (NMR, MS) and chemical methods. Eleven compounds were isolated and identified as 4'-0-(-) methylepigallocatechin (1),3,4-dimethoxyphenyl-beta-D-glucopyranoside (2), 3,4,5-trimethoxyphenyl-f-D-glucopyranoside (3), (2R,3R)-3,5,7,3',5'-pentahydroxyflavan (4), 2-O-deacetyleuonine (5), tripfordine C (6), peritassine A (7) hypoglaunine C (8), wilfortrine (9), wilforgine (10) and wilfordine (11). Compounds 1-6 are isolated from this plant for the first time.

Citation

Fu-Gui Xie, Chuang-Jun Li, Jing-Zhi Yang, Yong-Ming Luo, Dong-Ming Zhang. Study on chemical constituents from the root bark of Tripterygium hypoglaucum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2012 Jul;35(7):1083-7