A case of corneal endotheliitis with mumps virus RNA in aqueous humor detected by rt-PCR.

To report a case of corneal endotheliitis following the mumps parotitis. A 46-year-old man noticed ciliary infection and visual loss in the right eye after mumps parotitis. To determine the cause of the disease, reverse transcription-polymerase chain reaction (RT-PCR) was used to amplify mumps virus RNA in samples from the aqueous humor. RT-PCR revealed mumps virus RNA in an aqueous humor sample. Although full recovery of vision was achieved within 1 month of the onset, corneal endothelial cells were severely damaged. The authors have detected mumps virus in the aqueous humor by RT-PCR for the first time.

Citation

Kiyomu Ando, Mami Ishihara, Yoshifumi Kusumoto, Etsuko Shibuya, Satoshi Nakamura, Nobuhisa Mizuki. A case of corneal endotheliitis with mumps virus RNA in aqueous humor detected by rt-PCR. Ocular immunology and inflammation. 2013 Apr;21(2):150-2

PMID: 23252654

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