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African Americans have an endothelial dysfunction that likely contributes to their high prevalence of hypertension. Endothelial cell (EC) responses to stimuli could play a role in the development of endothelial dysfunction and hypertension. High physiological levels of vascular laminar shear stress can alter EC phenotype profoundly. It is not known whether there are race-dependent EC responses to laminar shear stress.


Michael D Brown, Deborah L Feairheller. Are there race-dependent endothelial cell responses to exercise? Exercise and sport sciences reviews. 2013 Jan;41(1):44-54

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PMID: 23262464

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