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Spindle orientation plays a pivotal role in tissue morphogenesis. An asymmetric anthrax receptor cap is revealed to promote activation of a formin to orient the spindle along the planar cell polarity (PCP) axis in zebrafish dorsal epiblast cells.

Citation

Nicolas Minc, Matthieu Piel. Anthrax receptors position the spindle. Nature cell biology. 2013 Jan;15(1):11-3

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PMID: 23263369

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