Acute miliary tuberculosis or Isambert disease: a case report].

Pharynx tuberculosis consists in a set of active lesions in granulomatous-type mucosa, resulting from Mycobacterium tuberculosis infection. In an endemic context, this diagnosis should be raised in cases of head and neck disease. A recent observation of a case of acute miliary tuberculosis gave us the opportunity to conduct a literature review of this disorder. This 9-year-old girl presented with dysphagia associated with pharyngeal discomfort, snoring, and hoarseness lasting for 8 months. This pharyngeal syndrome occurred in the context of an impaired general condition. Clinical examination found a diffuse mucosal granulation aspect in the oropharynx. The workup showed an inflammatory syndrome with a strong positive intradermal tuberculin reaction. The biopsy found an aspect of giant cell granuloma with caseous necrosis. The course was favorable on antituberculous chemotherapy. Tuberculosis is a chronic bacterial infection caused by a bacterium belonging to the M. tuberculosis complex. Pharyngeal tuberculosis remains a rare disease, but several epidemiological parameters show an upsurge of this disease, prompting us to report this observation. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

Citation

T Ziad, H Nouri, A Adny, Y Rochdi, L Aderdour, A Raji. Acute miliary tuberculosis or Isambert disease: a case report]. Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie. 2013 Jan;20(1):41-3

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PMID: 23266174

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