Dramatic reduction of proteinuria in diabetic nephropathy by the use of spironolactone.

Harry W Floyd

Journal of the South Carolina Medical Association (1975) 2012 Aug

filter terms:

The addition of spironolactone to the combination of an ACE inhibitor, and ARB, and a direct renin inhibitor brought about dramatic and sustained reversal of 4-plus proteinuria in a patient with diabetes mellitus and hypertension. Spironolactone may be a valuable addition to the therapeutic armamentarium for such patients, with the caveat that the spironolactone dose should be increased gradually and with frequent monitoring of the serum potassium level.

Citation

Harry W Floyd. Dramatic reduction of proteinuria in diabetic nephropathy by the use of spironolactone. Journal of the South Carolina Medical Association (1975). 2012 Aug;108(4):93-4