Photo-assisted cyanation of transition metal nitrates coupled with room temperature C-C bond cleavage of acetonitrile.

Shihui Zou, Renhong Li, Hisayoshi Kobayashi, Juanjuan Liu, Jie Fan

Key Lab of Applied Chemistry of Zhejiang Province, Department of Chemistry, Zhejiang University, Hangzhou, China.

Chemical communications (Cambridge, England) 2013 Mar 7

filter terms:

It is a challenge to use acetonitrile as a cyanating agent because of the difficulty in cleaving its C-CN bond. Herein, we report a mild photo-assisted route to conduct the cyanation of transition metal nitrates using acetonitrile as the cyanating agent coupled with room-temperature C-C bond cleavage. DFT calculations and experimental observations suggest a radical-involved reaction mechanism, which excludes toxicity from free cyanide ions.

Citation

Shihui Zou, Renhong Li, Hisayoshi Kobayashi, Juanjuan Liu, Jie Fan. Photo-assisted cyanation of transition metal nitrates coupled with room temperature C-C bond cleavage of acetonitrile. Chemical communications (Cambridge, England). 2013 Mar 7;49(19):1906-8