Vesicoureteral reflux and urodynamic dysfunction.

The concept of vesicoureteral reflux (VUR) as a consequence of congenital anomaly of vesicoureteral junction has undergone changes owing to the finding that such children may have lower urinary tract dysfunction, which produces high intravesical pressure and consequently a predisposition for VUR. The urodynamics was investigated by pressure-flow-EMG study in 132 children with VUR and 162 refluxing units. Only 33 (25.0%) patients had normal urodynamic finding. The most frequent pathological finding was overactive bladder (OAB), found in 59 (44.7%) children, followed by dysfunctional voiding (DV) in 25 (18.9%) children. Children with VUR grades I and II had a higher percentage of pathological urodynamic findings than children with VUR grades III and IV. OAB was more frequent in children under 5 years of age with unilateral and lower grade VUR. It was found equally in children with and without uroinfections. DV was more frequent in children older than 5 years, with bilateral VUR, higher grade VUR and uroinfections. Children with VUR have a high incidence of urodynamic disorders. The results of the study indicate the possible role of urodynamic dysfunction in the pathogenesis of VUR, especially mild one. Copyright © 2012 S. Karger AG, Basel.

Citation

Danica Batinic, Danko Miloševic, Marija Topalovic-Grkovic, Ljiljana Nizic, Kristina Vrljicak, Danko Batinic, Daniel Turudic. Vesicoureteral reflux and urodynamic dysfunction. Urologia internationalis. 2013;90(4):480-3

PMID: 23295895

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