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Prostate cancer responds well to androgen depletion therapy(ADT). However, when ADT was initiated on advanced prostate cancer, many become Castration-Resistant Prostate Cancer(CRPC)within a few years. Thus, development of new agents against CRPC is warranted. At the 2012 ASCO Meeting, results from two global randomized trials were given a warm reception. One trial involved abiraterone acetate and the other MDV3100.

Citation

Hideyuki Akaza. Epoch making development of new drugs for prostate cancer]. Gan to kagaku ryoho. Cancer & chemotherapy. 2013 Jan;40(1):30-4

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PMID: 23306917

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