Hepatitis in an infant treated with octreotide for congenital hyperinsulinism.

Ilana Koren, Arieh Riskin, Winfried Barthlen, David Gillis

Armon Child Center, Haifa, Israel. ilanaza2@clalit.org.il

Journal of pediatric endocrinology & metabolism : JPEM 2013

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Congenital hyperinsulinism is characterized by hypoglycemia caused by several genetic disorders of inappropriate insulin secretion. Octreotide, an analogue of somatostatin, plays a major role in the pharmaceutical treatment of this condition. A 9-month-old infant treated with octreotide developed anicteric hepatitis with no other proven cause. After the discontinuation of this drug, the liver enzymes declined rapidly. Liver function tests should be followed in patients receiving octreotide.

Citation

Ilana Koren, Arieh Riskin, Winfried Barthlen, David Gillis. Hepatitis in an infant treated with octreotide for congenital hyperinsulinism. Journal of pediatric endocrinology & metabolism : JPEM. 2013;26(1-2):183-5