Bifunctional gene cluster lnqBCDEF mediates bacteriocin production and immunity with differential genetic requirements.

Shun Iwatani, Yuko Horikiri, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

Applied and environmental microbiology 2013 Apr

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A comprehensive gene disruption of lacticin Q biosynthetic cluster lnqQBCDEF was carried out. The results demonstrated the necessity of the complete set of lnqQBCDEF for lacticin Q production, whereas immunity was flexible, with LnqEF (ABC transporter) being essential for and LnqBCD partially contributing to immunity.

Citation

Shun Iwatani, Yuko Horikiri, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto. Bifunctional gene cluster lnqBCDEF mediates bacteriocin production and immunity with differential genetic requirements. Applied and environmental microbiology. 2013 Apr;79(7):2446-9