Current research status on radiation retinopathy].

Radiation retinopathy (RR) and radiation optic neuropathy (RON) are vision-threatening complications of head and/or neck irradiation therapy. Clinical features are characterized by delayed-onset, slowly progressive, occlusive vasculopathy caused by endothelial damage. Compared with the optic nerve, retinal vessels are more sensitive and harmful to radioactive injury and cause RR, which may progress to eyeball atrophy ultimately. Thorough understanding of the incidence, pathogenesis, risk factors, clinical characteristics and treatment of RR is of practice significance. Ongoing basic laboratory and clinical research efforts have led to a better understanding of this disease. This article reviews the present research status of RR briefly.

Citation

Wei Wang, Xiu-lan Zhang, Shi-hui Wei. Current research status on radiation retinopathy]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. 2012 Dec;48(12):1132-5

PMID: 23336419

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