Ductal adenocarcinoma of the prostate: a report of 7 cases].

Ductal adenocarcinoma of the prostate is a rare subtype of prostatic adenocarcinoma, defined by morphological criteria as one that has papillary or cribriform architecture composed of high columnar cells with pseudostratified nuclei. We clinically evaluated 7 cases of ductal adenocarcinoma of the prostate in our hospital. The median age was 69 years old and median initial serum PSA level was 22.8 ng/ml. Two cases presented with dysuria, two with macrohematuria and one with abnormality on chest radiograph. Five cases were diagnosed on prostate biopsy, one on TUR-P and one on radical prostatectomy. Two had pure ductal adenocarcinoma and five had mixed ductal adenocarcinoma. Four had metastatic disease, and were treated by hormonal therapy. Among three with non-metastatic disease, two underwent radical prostatectomy with adjuvant radiotherapy and one underwent external beam radiotherapy with hormonal therapy. Three cases with non-metastatic disease have no biochemical recurrence. Among four with metastatic disease, one underwent chemotherapy of Docetaxel and one had found a new lesion in lung.

Citation

Kanae Hiramatsu, Yasuo Tsuzaka, Tomoyuki Kaneko, Hisashi Matsushima, Yukio Homma. Ductal adenocarcinoma of the prostate: a report of 7 cases]. Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology. 2012 Sep;103(5):671-4

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PMID: 23342927

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