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Thiourea-catalyzed aminolysis of N-acyl homoserine lactones.
Michael A Bertucci, Stephen J Lee, Michel R Gagné
Department of Chemistry, University of North Carolina at Chapel Hill, Campus Box 3290, Caudill and Kenan Laboratories, Chapel Hill, NC 27599-3290, USA.
Chemical communications (Cambridge, England) 2013 Mar 11Sizes of these terms reflect their relevance to your search.
Thiourea catalysts accelerate aminolysis of N-acyl homoserine lactones (AHLs), molecules integral to bacterial quorum sensing. The catalysts afford rate enhancement of up to 10 times the control in CD(3)CN. Mild catalysis in other polar aprotic solvents is still observed, while the activity is attenuated in polar protic solvents.
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Michael A Bertucci, Stephen J Lee, Michel R Gagné. Thiourea-catalyzed aminolysis of N-acyl homoserine lactones. Chemical communications (Cambridge, England). 2013 Mar 11;49(20):2055-7
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PMID: 23376901
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