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The endoplasmic reticulum (ER) is a heterogeneous organelle with distinct morphologies of sheets and an interconnected network of tubules sharing a common lumen. An ER domain marked by the Rab10 GTPase and several lipid-synthesizing enzymes is implicated in dynamic ER tubule formation and fusion events in cells.

Citation

Jaerak Chang, Craig Blackstone. Rab10 joins the ER social network. Nature cell biology. 2013 Feb;15(2):135-6

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PMID: 23377026

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