When the drugs don't work: the potential of glutamatergic antipsychotics in schizophrenia.

Evangelos Papanastasiou, James M Stone, Sukhi Shergill

The British journal of psychiatry : the journal of mental science 2013 Feb

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Currently available antipsychotic drugs target dopaminergic neurotransmission. Many patients do not respond fully to these treatments, and there has been considerable effort to investigate alternative targets. Here we summarise the rationale and recent evidence supporting efforts to develop glutamatergic antipsychotic drugs.

Citation

Evangelos Papanastasiou, James M Stone, Sukhi Shergill. When the drugs don't work: the potential of glutamatergic antipsychotics in schizophrenia. The British journal of psychiatry : the journal of mental science. 2013 Feb;202:91-3