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This article describes a novel approach to teaching novice Biochemistry students visual literacy skills and understanding of some aspects of protein structure using the internet resource FoldIt and a worksheet based on selected Introductory Puzzles from this computer game. In responding to a questionnaire, students indicated that they (94%) enjoyed playing the game and furthermore, they indicated that they (100%) perceived an improvement in their understanding of protein structure as a result. Instructor observation of the students using the game together with the worksheet corroborated the results of the student perception survey. Copyright © 2012 International Union of Biochemistry and Molecular Biology, Inc.


Peter C Farley. Using the computer game "FoldIt" to entice students to explore external representations of protein structure in a biochemistry course for nonmajors. Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology. 2013 Jan-Feb;41(1):56-7

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PMID: 23382128

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