Modified Hodge test versus indirect carbapenemase test: prospective evaluation of a phenotypic assay for detection of Klebsiella pneumoniae carbapenemase (KPC) in Enterobacteriaceae.

Amy J Mathers, Joanne Carroll, Costi D Sifri, Kevin C Hazen

Journal of clinical microbiology 2013 Apr

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The currently recommended phenotypic test for the detection of carbapenemase-producing members of the family Enterobacteriaceae is the modified Hodge test (MHT). However, the MHT lacks specificity. Here we demonstrate an alternative phenotypic test, the indirect carbapenemase test, for the detection of blaKPC-producing isolates that has specificity superior to that of the MHT for non-Klebsiella Enterobacteriaceae.

Citation

Amy J Mathers, Joanne Carroll, Costi D Sifri, Kevin C Hazen. Modified Hodge test versus indirect carbapenemase test: prospective evaluation of a phenotypic assay for detection of Klebsiella pneumoniae carbapenemase (KPC) in Enterobacteriaceae. Journal of clinical microbiology. 2013 Apr;51(4):1291-3