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Microbiology: EHEC downregulates virulence in response to intestinal fucose.

Kristie M Keeney, B Brett Finlay

Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.

Current biology : CB 2013 Feb 4


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    Recent work has revealed that enterohaemorrhagic Escherichia coli encodes a two-component system, termed FusKR, which responds to fucose and represses expression of virulence genes. Furthermore, a representative member of the microbiota appears to cleave fucose from host glycans, indicating that the microbiota and EHEC may act in concert to suppress virulence gene expression. Copyright © 2013 Elsevier Ltd. All rights reserved.

    Citation

    Kristie M Keeney, B Brett Finlay. Microbiology: EHEC downregulates virulence in response to intestinal fucose. Current biology : CB. 2013 Feb 4;23(3):R108-10

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    PMID: 23391383

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