The role of kidney in pathogenesis of arterial hypertension].

Katedra i Klinika Nefrologii, Uniwersytet Jagielloński, Collegium Medicum w Krakowie.

Przegla̧d lekarski 2012

Blood pressure control is regulated by complicated physiological mechanisms, which are dependent upon cardio-vascular, neurological, endocrine systems and the kidneys. The kidneys plays an important role in the regulation of blood pressure based on sodium and water balance, renin-an. giotensin-aldosterone axis, sympathetic activity as well as other regulatory substances like: natriuretic peptides (ANP, BNP) endothelin, dopamine, prostaglandins and nitric oxide (NO). In chronic kidney disease (CKD) patients hypertension is extremely common and is aggravated together with the lowering of renal clearance (GFR). The kidneys may be a cause and a culprit of hypertension.