Synthesis of LipidGreen2 and its application in lipid and fatty liver imaging.

Hang-Suk Chun, Jong Hyun Jeon, Haushabhau S Pagire, Jae Hong Lee, Hee-Chung Chung, Myoung Joo Park, Ju-Hoon So, Jae-Ho Ryu, Cheol-Hee Kim, Jin Hee Ahn, Myung Ae Bae

Bioorganic Science Division, Korea Research Institute of Chemical Technology, Jang-Dong 100, Yuseong, Daejeon, 305-600, South Korea.

Molecular bioSystems 2013 Apr 5

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We have developed LipidGreen2, a second generation small molecule probe for lipid imaging. LipidGreen2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish. We also demonstrate the application of LipidGreen2 for detecting fatty liver.

Citation

Hang-Suk Chun, Jong Hyun Jeon, Haushabhau S Pagire, Jae Hong Lee, Hee-Chung Chung, Myoung Joo Park, Ju-Hoon So, Jae-Ho Ryu, Cheol-Hee Kim, Jin Hee Ahn, Myung Ae Bae. Synthesis of LipidGreen2 and its application in lipid and fatty liver imaging. Molecular bioSystems. 2013 Apr 5;9(4):630-3