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Design of a platinum-acridine-endoxifen conjugate targeted at hormone-dependent breast cancer.
Chemical communications (Cambridge, England) 2013 Mar 25Sizes of these terms reflect their relevance to your search.
The synthesis of a novel pharmacophore comprising a DNA-targeted platinum-acridine hybrid agent and estrogen receptor-targeted 4-hydroxy-N-desmethyltamoxifen (endoxifen) using carbamate coupling chemistry and its evaluation in breast cancer cell lines are described.
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Song Ding, Xin Qiao, Gregory L Kucera, Ulrich Bierbach. Design of a platinum-acridine-endoxifen conjugate targeted at hormone-dependent breast cancer. Chemical communications (Cambridge, England). 2013 Mar 25;49(24):2415-7
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PMID: 23416453
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