Three new norlignans from Glechoma longituba.

Qiu-Fang Zhu, Yong-Yi Wang, Wei Jiang, Hai-Bin Qu

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

Journal of Asian natural products research 2013

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Three new norlignans, glechomols A-C (1-3, respectively), together with a known compound, 4-ethylcatechol (4), were isolated from the ethyl acetate extract of Glechoma longituba (NaKai) Kupr. Their structures were elucidated by the detailed analysis of 1D and 2D NMR and HR-MS data. Glechomols A-C were the first norlignans reported from genus Glechoma, and compound 4 was also isolated from genus Glechoma for the first time. Intracellular antioxidant assays showed that compounds 1-4 displayed significant protective effects on H2O2-induced cardiac cell injury.

Citation

Qiu-Fang Zhu, Yong-Yi Wang, Wei Jiang, Hai-Bin Qu. Three new norlignans from Glechoma longituba. Journal of Asian natural products research. 2013;15(3):258-64