Circulating immune complexes, heat shock proteins in the serum of smoking allergy sufferers--preliminary results].

Circulating immune complexes (CIC) rises in response to immunogens appearing in human body. An increasing of the CIC concentration is observed in allergies as well as many others diseases. As a result of inflammatory process localized within intracellular space heat shock proteins (HSP) may occur. The aim of work was the CIC levels estimation as well as CIC HSP-70 presence analysis in serum of smoking and non-smoking allergy sufferers. Serum from 12 smoking and 15 non-smoking patients were examined. Serum from 34 healthy persons constituted the control group. The level of CIC was established by Haskowa precipitation method. The identification of HSP-70 antigen within CIC was determined by Dot blot method. We discovered increased CIC levels in serum from smoking allergy sufferers in comparison with non-smokers. The highest percentage of HSP-70 presence within CIC was observed in smoking allergy sufferers.

Citation

Ryszard Gołda, Grzegorz Przybylski, Wojciech Jóźwicki, Małgorzata Wyszomirska. Circulating immune complexes, heat shock proteins in the serum of smoking allergy sufferers--preliminary results]. Przegla̧d lekarski. 2012;69(10):737-9

Mesh Tags

Substances

PMID: 23421022

search → result