Toxic effects of copper ion in zebrafish in the joint presence of CdTe QDs.

Wei Zhang, Youna Miao, Kuangfei Lin, Lin Chen, Qiaoxiang Dong, Changjiang Huang

State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, East China University of Science and Technology, Shanghai 200237, PR China. wzhang@ecust.edu.cn

Environmental pollution (Barking, Essex : 1987) 2013 May

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Quantum dots (QDs) have strong adsorption capacity; therefore, their potential toxicity of the facilitated transport of other trace toxic pollutants when they co-exist to aquatic organisms has become a hot research topic. The lab study was performed to determine the developmental toxicities to the zebrafish after exposed to the combined pollution of Cadmium-telluride (CdTe) QDs and copper ion (Cu(2+)) compared to the single exposure. Our findings for the first time revealed that: 1) CdTe QDs facilitated the accumulation of Cu(2+) in zebrafish, 2) the higher mortality, lower hatch rate, and more malformations can be clearly observed, 3) the diverse vascular hyperplasia, turbulence, and bifurcation of the exposed FLI-1 transgenic zebrafish larvae appeared together, 4) the synergistic effects played more important role during joint exposure. These observations provide a basic understanding of CdTe QDs and Cu(2+) joint toxicity to aquatic organisms. Copyright © 2013 Elsevier Ltd. All rights reserved.

Citation

Wei Zhang, Youna Miao, Kuangfei Lin, Lin Chen, Qiaoxiang Dong, Changjiang Huang. Toxic effects of copper ion in zebrafish in the joint presence of CdTe QDs. Environmental pollution (Barking, Essex : 1987). 2013 May;176:158-64