Clinical outcomes associated with procalcitonin algorithms to guide antibiotic therapy in respiratory tract infections.

Philipp Schuetz, Matthias Briel, Beat Mueller

Medical University Department, Kantonsspital Aarau, Tellstrasse, CH-5001 Aarau, Switzerland. schuetzph@gmail.com

JAMA : the journal of the American Medical Association 2013 Feb 20

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In patients with respiratory tract infection, is measurement of procalcitonin to guide antibiotic prescriptions associated with reduced antibiotic exposure without increases in all-cause mortality or treatment failure? The measurement of procalcitonin to guide initiation and duration of antibiotic treatment in patients with respiratory tract infections of varying severity is associated with lower antibiotic exposure without increasing all-cause mortality or treatment failure.

Citation

Philipp Schuetz, Matthias Briel, Beat Mueller. Clinical outcomes associated with procalcitonin algorithms to guide antibiotic therapy in respiratory tract infections. JAMA : the journal of the American Medical Association. 2013 Feb 20;309(7):717-8