Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells.

Lorraine Blackmore, Roisin Moriarty, Ciaran Dolan, Kellie Adamson, Robert J Forster, Marc Devocelle, Tia E Keyes

National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Dublin 9, Ireland.

Chemical communications (Cambridge, England) 2013 Apr 4

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The targeted delivery of luminescent Ru(II) polypyridyl complexes to the nucleus of live mammalian cells by a Nuclear Localisation Signal (NLS) peptide; NF-κB is demonstrated.

Citation

Lorraine Blackmore, Roisin Moriarty, Ciaran Dolan, Kellie Adamson, Robert J Forster, Marc Devocelle, Tia E Keyes. Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells. Chemical communications (Cambridge, England). 2013 Apr 4;49(26):2658-60