Tuberculous meningitis: a report of 60 adult cases.

M Ersöz, M T Yildirmak, H Gedik, F Simşek, A Kantürk, N E Iris, E Dinç

Department of Infectious Diseases and Clinical Microbiology, Minsitry of Health Okmeydani Training and Research Hospital, Istanbul, Turkey.

The West Indian medical journal 2012 Sep

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This was to evaluate the history, clinical and laboratory findings, outcome and prognosis of patients with tuberculous meningitis (TBM). Between 1998 and 2009, 60 patients with TBM were evaluated, retrospectively. Overall, 60 patients were selected, of which 33 (55%) were male. The patients' ages ranged from 14 to 62 years. In the majority of the patients, disease was in an advanced stage on admission (66% in stage III according to the British Research Council neurological criteria). The rate of complications was highest among patients in stages II and III with an overall mortality rate of 6.6% (n = 2 of stage II patients and n = 2 of stage III patients). Earlier admission of the patients with TBM could provide better outcomes with regard to sequelae and mortality. Fatal cases presented with rapid deterioration and were refractory to treatment.

Citation

M Ersöz, M T Yildirmak, H Gedik, F Simşek, A Kantürk, N E Iris, E Dinç. Tuberculous meningitis: a report of 60 adult cases. The West Indian medical journal. 2012 Sep;61(6):592-7