Holoprosencephaly in clomiphene-induced pregnancy: a possible association? A case report and literature review.

Poison Control Centre and Teratology Information Service, Ospedali Riuniti, Bergamo, Italy. geleftheriou@ospedaliriuniti.bergamo.it

Clinical and experimental obstetrics & gynecology 2012

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Clomiphene is widely used for inducing ovulation. Evidence for congenital abnormalities, in particular central nervous system defects (CNS-D) and in babies born from clomiphene-induced pregnancies is conflicting. The authors report a case of holoprosencephalia (HPE) in a fetus delivered from a mother receiving clomiphene.

Citation

G Eleftheriou, R Butera, L Manzo. Holoprosencephaly in clomiphene-induced pregnancy: a possible association? A case report and literature review. Clinical and experimental obstetrics & gynecology. 2012;39(4):535-6