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Synthetic and structure-activity relationship studies on bioactive natural products.
Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Japan. kuramoch@kpu.ac.jp
Bioscience, biotechnology, and biochemistry 2013Sizes of these terms reflect their relevance to your search.
This review summarizes our research into the synthesis and structure-activity relationships of epolactaene, neoechinulin A, plakevulin A, pseudodeflectusin and ustusorane C. These natural products are attractive in view of their apoptosis-inducing activity, cytoprotective activity against peroxynitrite, inhibitory activity against DNA polymerases, and cytotoxicity in cancer cells.
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Kouji Kuramochi. Synthetic and structure-activity relationship studies on bioactive natural products. Bioscience, biotechnology, and biochemistry. 2013;77(3):446-54
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PMID: 23470748
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