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Synthetic and structure-activity relationship studies on bioactive natural products.

Kouji Kuramochi

Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Japan. kuramoch@kpu.ac.jp

Bioscience, biotechnology, and biochemistry 2013


filter terms:
  • activity (3)
  • animals (1)
  • apoptosis (1)
  • biological agents (2)
  • cells (1)
  • dna polymerases (1)
  • epolactaene (1)
  • humans (1)
  • natural products (2)
  • neoechinulin a (1)
  • organic chemicals (2)
  • peroxynitrite (1)
  • plakevulin a (1)
  • pseudodeflectusin (1)
  • structure activity relationship (3)
  • ustusorane c (1)
    • Sizes of these terms reflect their relevance to your search.

    This review summarizes our research into the synthesis and structure-activity relationships of epolactaene, neoechinulin A, plakevulin A, pseudodeflectusin and ustusorane C. These natural products are attractive in view of their apoptosis-inducing activity, cytoprotective activity against peroxynitrite, inhibitory activity against DNA polymerases, and cytotoxicity in cancer cells.

    Citation

    Kouji Kuramochi. Synthetic and structure-activity relationship studies on bioactive natural products. Bioscience, biotechnology, and biochemistry. 2013;77(3):446-54

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    PMID: 23470748

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